TGIF1 Antibody (YA7822)
(Synonyms: HPE4; TGIF)TGIF1 Antibody (YA7822) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TGIF1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
TGIF1 Antibody (YA7822) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TGIF1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 29.6 kDa
Full length human recombinant protein of human TGIF1 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
TGIF1 binds to a retinoid X receptor (RXR) responsive element from the cellular retinol-binding protein II promoter (CRBPII-RXRE). Inhibits the 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element. Active transcriptional corepressor of SMAD2. Links the nodal signaling pathway to the bifurcation of the forebrain and the establishment of ventral midline structures. May participate in the transmission of nuclear signals during development and in the adult, as illustrated by the down-modulation of the RXR alpha activities
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Subcellular Localization
Nucleus
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Isoforms & Post-Translational Modification
Q15583 has four isomers: Q15583-1: 43013 Da (predicted); Q15583-2: 29737 Da (predicted); Q15583-3: 31064 Da (predicted); Q15583-4: 27715 Da (predicted).
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Subunit
Interacts with SMAD2 (PubMed:10835638)
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SwissProt ID
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Synonyms
HPE4; TGIF
Documentation
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