TIMM23 Antibody (YA8810)(PBS only)
(Synonyms: TIM23)TIMM23 Antibody (YA8810) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to TIMM23.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:5000-1500 |
Product Details
TIMM23 Antibody (YA8810) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to TIMM23.
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Host Mouse
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 21.8 kDa
Full length human recombiant protein of human TIMM23 produced in E.coli.
Affinity purified
Non-conjugated
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
TIMM23 is essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has a role in the activation of stress-induced mitophagy by protecting PINK1 from OMA1-mediated degradation and facilitating its accumulation at the outer mitochondrial membrane in response to depolarization[1][2].
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Subcellular Localization
Mitochondrion inner membrane
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Isoforms & Post-Translational Modification
O14925: 209 amino acids, molecular weight 21943 Da.
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Subunit
Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50; within this complex, directly interacts with TIMM50 (PubMed:15044455)
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SwissProt ID
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Synonyms
TIM23
Documentation
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