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XPF Antibody (YA9958) (PBS Only)

(Synonyms: ERCC11; FANCQ; RAD1; XFEPS; XPF)

XPF Antibody (YA9958) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to XPF.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2a

  • Application:

    WB, ICC/IF, FC

  • Reactivity :

    Human, Dog, Rat, Monkey, Mouse

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • XPF Antibody (YA9958) (PBS Only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Service
Data Download
Top Publications Citing

Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:500-2000 1:100-200 1:100

Product Details

Description

XPF Antibody (YA9958) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to XPF.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human, Dog, Rat, Monkey, Mouse
  • Calculated Molecular Weight Predicted band size: 104.3kDa
Immunogen

Full length human recombinant protein of human ERCC4 produced in HEK293 cell.

Sensitivity

Endogenous

Purification

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG2a

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    XPF is a Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair, and which is essential for nucleotide excision repair (NER) and interstrand cross-link (ICL) repair

  • Subcellular Localization

    Nucleus,Chromosome

  • Isoforms & Post-Translational Modification

    XPF has two isomers: Q92889-1: 104486 Da (predicted); Q92889-2: 42745 Da (predicted).
    Acetylation at Lys-911 by KAT5 promotes interaction with ERCC1 by disrupting a salt bridge between Glu-907 and Lys-911, thereby exposing a second binding site for ERCC1

  • Subunit

    Heterodimer composed of ERCC1 and ERCC4/XPF

  • SwissProt ID

    Q92889

  • Synonyms

    ERCC11; FANCQ; RAD1; XFEPS; XPF

XPF Antibody (YA9958) (PBS Only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • XPF Antibody (YA9958) (PBS Only) Product Image
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  • XPF Antibody (YA9958) (PBS Only) Product Image