YKL-40/CHI3L1 Antibody (YA6959)

Cat. No.: HY-P87276: Data Sheet COA
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User Guide for Antibodies
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YKL-40/CHI3L1 Antibody (YA6959) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to YKL-40/CHI3L1.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

사이즈	재고	수량
10 μL	해외재고보유	Estimated Time of Arrival: December 31
50 μL	해외재고보유	Estimated Time of Arrival: December 31
100 μL	해외재고보유	Estimated Time of Arrival: December 31
250 μL	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

YKL-40/CHI3L1 Antibody (YA6959) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to YKL-40/CHI3L1.

Host

Mouse

Clonality

Monoclonal

분자량

Predicted band size: 43 kDa;

Observed band size: 43 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P36222

Immunogen

Recombinant protein within extracellular domain of Human CHI3L1.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:200

Sensitivity	Endogenous	Purity	Protein G affinity purified.
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2a

Appearance

Liquid

Formulation

Supplied in 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung

Subcellular Localization：Secreted, extracellular space,Cytoplasm,Cytoplasm, perinuclear region,Endoplasmic reticulum

Expression：
Tissue_Specificity: Present in activated macrophages, articular chondrocytes, synovial cells as well as in liver. Very low or undetectable expression in non-inflammatory colon. Undetectable in muscle tissues, lung, pancreas, mononuclear cells, or fibroblasts
Induction: Up-regulated in colon under several inflammatory conditions. Down-regulated by hyperoxia in bronchial epithelial cells

Subunit：Monomer

Synonyms

39 kDa synovial protein antibody; ASRT7 antibody; Cartilage glycoprotein 39 antibody; CGP-39 antibody; CGP39 antibody; CH3L1_HUMAN antibody; CHI3L1 antibody; chitinase 3 like 1 (cartilage glycoprotein 39) antibody; chitinase 3 like 1 antibody; Chitinase 3 like protein 1 precursor antibody

각종 서류

Select Batch:

Data Sheet (231 KB) SDS (252 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)