RASSF4 - Ras association domain family member 4 Gene

Also Known as AD037

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 83937

About RASSF4

Cytogenetic location: 10q11.21 Genomic coordinates (GRCh38): 10:44,959,802-44,995,891 (from NCBI)

This gene has 12 transcripts (splice variants), 171 orthologues and 5 paralogues. Ubiquitous expression in brain (RPKM 36.2), fat (RPKM 31.7) and 25 other tissues.

Summary

The function of this gene has not yet been determined but may involve a role in tumor suppression. Alternative splicing of this gene results in several transcript variants; however, most of the variants have not been fully described. [provided by RefSeq, Jul 2008]

RASSF4 Products (1)

mRNA Protein Name
NM_032023.4 NP_114412.2 ras association domain-containing protein 4

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
20562859 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RASSF4 Protein Structure

RA

RA: Ras association (RalGDS/AF-6) domain (178 - 259)

  • 0
  • 100
  • 200
  • 300
  • 321 a.a.
Protein Preferred Names Protein Names

ras association domain-containing protein 4

  • Ras association (RalGDS/AF-6) domain family 4

RASSF4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
RASSF4 Q9H2L5 CENPH Homo sapiens Q9H3R5
Validated Y2H
32296183
Intra
RASSF4 Q9H2L5 MAGEA6 Homo sapiens P43360
Y2H Prey Pooling
32296183
Intra
RASSF4 Q9H2L5 MAGEA6 Homo sapiens P43360
Y2H Array
32296183
Intra
RASSF4 Q9H2L5 STK4 Homo sapiens Q13043
Anti Tag CoIP
20920251
Intra
RASSF4 Q9H2L5 STK4 Homo sapiens Q13043
Anti Tag CoIP
24366813
Intra
RASSF4 Q9H2L5 IFT20 Homo sapiens Q8IY31-3
Y2H Prey Pooling
32296183
Intra
RASSF4 Q9H2L5 IFT20 Homo sapiens Q8IY31-3
Y2H Array
32296183
Intra
RASSF4 Q9H2L5 STK3 Homo sapiens Q13188
Y2H Array
25416956
Intra
RASSF4 Q9H2L5 STK3 Homo sapiens Q13188
Anti Tag CoIP
24366813
Intra
RASSF4 Q9H2L5 STK3 Homo sapiens Q13188
Y2H
20920251
Intra
RASSF4 Q9H2L5 STK3 Homo sapiens Q13188
Y2H Prey Pooling
25416956
Intra
RASSF4 Q9H2L5 STK3 Homo sapiens Q13188
Validated Y2H
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-112056 DIM-C-pPhCO2Me 99.47% Unkown
HY-RS11704 RASSF4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11983 RIN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21918 Rassf4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28434 Rassf4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta RASSF4 VGNC VGNC:76514
Bos taurus RASSF4 VGNC VGNC:33760
Rattus norvegicus RASSF4 RGD RGD:1307785
Mus musculus RASSF4 MGD MGI:2386853
Felis catus RASSF4 VGNC VGNC:64507
Canis familiaris RASSF4 VGNC VGNC:45381
Others RASSF4 NCBI