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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
218 Results for "
EC 2.4.1
" in MedChemExpress (MCE) Product Catalog:
Products (218)
218 Results for "EC 2.4.1" in MCE Product Catalog:
Art. -Nr.: HY-179095
CAS. Nr.: 2597345-07-6
Forschungsgebiete:
UR241-2 is an IRAK4 inhibitor. UR241-2 suppresses IL-1–induced IRAK1/4 signaling, NF-κβ activation, and phosphorylation of p65 and p38. UR241-2 selectively inhibits leukemia stem cell clonogenicity. UR241-2 can serve as a ligand for target proteins for PROTAC, facilitating the development and design of PROTAC degraders for IRAK4. UR241-2 can be used in the research of acute myeloid leukemia .
Synonyms: C24:1 Deoxy dihydroceramide; C24:1 DeoxyDHceramide; Cer(m18:0/24:1)
Target:
Forschungsgebiete:
C24:1 Dihydro 1-deoxyceramide (m18:0/24:1) (C24:1 Deoxy dihydroceramide) is a lipid molecule, which is composed of a long-chain fatty acid (24:1) and a 1-deoxysphingoid backbone. Deoxyceramide accumulates under the conditions of obesity and type 2 diabetes (T2D). Deoxyceramide is unable to be further metabolized to more complex sphingolipid, and is toxic when accumulates in the body. Deoxyceramide increases in differentiated adipocytes in vitro .
Art. -Nr.: HY-116798
CAS. Nr.: 546141-07-5
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Forschungsgebiete:
URB524 is an irreversible FAAH inhibitor of O-aryl amino acid esters. URB524 inhibits FAAH by aminoformylation of Ser241. URB524 exhibits analgesic, antidepressant, and anti anxiety activity .
Art. -Nr.: HY-149912A
Forschungsgebiete:
CZS-241 hydrochloride is an orally active and selective inhibitor of Polo-like Kinase 4 (PLK4) (IC50=2.6 nM). CZS-241 hydrochloride inhibits TRKA with an IC50 value of 2.74 μM. CZS-241 hydrochloride induces apoptosis and arrests cell cycle at S/G2 phase. CZS-241 hydrochloride shows highly potent antiproliferative activity against leukemia cell lines, and exhibits safety against normal cell lines .
Art. -Nr.: HY-P990644
Target:
Forschungsgebiete:
Art. -Nr.: HY-34840
CAS. Nr.: 1142201-78-2
Target:
Forschungsgebiete:
6-Hydrazinyl-3-methylpyrimidine-2,4(1H,3H)-dione is a drug intermediate for synthesis of various active compounds.
Art. -Nr.: HY-P2495
CAS. Nr.: 2648610-97-1
Target:
Forschungsgebiete:
Art. -Nr.: HY-N15825
CAS. Nr.: 168780-25-4
Category:
Target:
Art. -Nr.: HY-E70143
Synonyms: EC:2.4.1.15; N-Acetylglucosaminyltransferase
Art. -Nr.: HY-W777583
CAS. Nr.: 1173019-61-8
Art. -Nr.: HY-W751834
CAS. Nr.: 2841166-05-8
Synonyms: NSC 99321-13C3; 6-Amino-5-nitrouracil-13C3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
