Antitumor agent-173
Antitumor agent-173 (Compound 4b) is a prodrug of Cycloicaritin (HY-N1940). Antitumor agent-173 is a substrate for OATP2B1. Antitumor agent-173 selectively inhibits the growth of tumor Antitumor agent-173 significantly increases the oral bioavailability of Cycloicaritin and exerts good antitumor activity and safety.
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- Formule: C28H31NO9
- Masse moléculaire:525.55
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NIH3T3 | IC50 |
>100 μM
Compound: 4b
|
Cytotoxicity against mouse 3T3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxicity against mouse 3T3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 38972080] |
Chemical Information
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Masse moléculaire 525.55
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Formule C28H31NO9
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SMILES
COC(C=C1)=CC=C1C2=C(OC(N[C@@H](CC(C)C)C(O)=O)=O)C(C3=C(O)C=C4C(CCC(C)(C)O4)=C3O2)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)