118931-00-3
118931-00-3
Chemical Structure
Abanoquil methylsulfate
Synonym(s): UK-52046 methylsulfate
- CAS No.: 118931-00-3
- Formula:C23H29N3O7S
- Molecular Weight:491.56
IUPAC Name: 2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-6,7-dimethoxyquinolin-4-amine methanesulfonate
InChIKey: FMDPOTBKJNHQLC-UHFFFAOYSA-N
SMILES: COC1=C(C=C2C(N)=CC(N3CC4=C(CC3)C=C(C(OC)=C4)OC)=NC2=C1)OC.O=S(C)(O)=O
Biological Activity: Abanoquil methylsulfate (UK-52046 methylsulfate) is an alpha-1 family adrenergic receptor antagonist. Abanoquil methylsulfate can be used in research on cardiovascular diseases such as arrhythmias and erectile dysfunction[1][2].
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Abanoquil methylsulfate | Abanoquil methylsulfate (UK-52046 methylsulfate) is an alpha-1 family adrenergic receptor antagonist. Abanoquil methylsulfate can be used in research on cardiovascular diseases such as arrhythmias and erectile dysfunction. | |||||||||||||||||||||
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References
- [1]. Giraldi A, et al. Abanoquil, a new alpha-1 adrenoceptor antagonist. In vitro and in vivo effect on erectile tissue. Int J Impot Res. 2000 Mar;12 Suppl 1:S37-40. [Content Brief]
- [2]. Tham TC, et al. Dose-dependent alpha 1-adrenoceptor antagonist activity of the anti-arrhythmic drug, abanoquil (UK-52,046), without reduction in blood pressure in man. Br J Clin Pharmacol. 1992 Apr;33(4):405-9. [Content Brief]
