2306302-57-6
2306302-57-6
Chemical Structure
SQS-IN-1
- CAS No.: 2306302-57-6
- Formula:C24H27BrN2O5
- Molecular Weight:503.39
SMILES: CN1CCOC(C2=CC=C(C3=CC=C(C=CC=C4)C4=C3)C=C2)(OCCCO[N+]([O-])=O)C1.Br
Biological Activity: SQS-IN-1 is a squalene synthase (SQS) inhibitor. SQS-IN-1 exhibits potent and broad-spectrum anti-proliferative effects on both mouse and human lung cancer cell lines. SQS-IN-1 inhibits DNA replication and the cell cycle, causing mitochondrial hyperpolarization and inducing cell apoptosis. SQS-IN-1 inhibits cell migration and invasion. SQS-IN-1 can be used to the study of lung cancer[1].
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SQS-IN-1 | SQS-IN-1 is a squalene synthase (SQS) inhibitor. SQS-IN-1 exhibits potent and broad-spectrum anti-proliferative effects on both mouse and human lung cancer cell lines. SQS-IN-1 inhibits DNA replication and the cell cycle, causing mitochondrial hyperpolarization and inducing cell apoptosis. SQS-IN-1 inhibits cell migration and invasion. SQS-IN-1 can be used to the study of lung cancer. | |||||||||||||||||||||
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