66471-20-3
66471-20-3
Chemical Structure
Bestim
Synonym(s): γ-Glu-Trp
- CAS No.: 66471-20-3
- Formula:C16H19N3O5
- Molecular Weight:333.34
IUPAC Name: N5-((S)-1-carboxy-2-(1H-indol-3-yl)ethyl)-L-glutamine
InChIKey: CATMPQFFVNKDEY-AAEUAGOBSA-N
SMILES: O=C([C@@H](NC(CC[C@H](N)C(O)=O)=O)CC1=CNC2=C1C=CC=C2)O
Biological Activity: Bestim (γ-Glu-Trp) is a dipeptide, which exhibits high affinity to murine peritoneal macrophages, thymocytes, and plasma membranes isolated from these cells, with Kds of 3.1, 2.1, 18.6 and 16.7 nM, respectively. Bestim inhibits adenylate cyclase in the membranes of murine macrophages and thymocytes. Bestim exhibits immunomodulatory efficacy[1].
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Bestim | 98.73% | Bestim (γ-Glu-Trp) is a dipeptide, which exhibits high affinity to murine peritoneal macrophages, thymocytes, and plasma membranes isolated from these cells, with Kds of 3.1, 2.1, 18.6 and 16.7 nM, respectively. Bestim inhibits adenylate cyclase in the membranes of murine macrophages and thymocytes. Bestim exhibits immunomodulatory efficacy. | ||||||||||||||||||||
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