PDE4-IN-9
PDE4-IN-9 (Compound 5j) is a potent inhibitor of PDE4. PDE4-IN-9 exhibits lower IC50 value (1.4 μM) against PDE4 than parent rolipram (2.0 μM) in in vitro enzyme assay. PDE4-IN-9 also displays good in vivo activity in animal models of asthma/COPD and sepsis induced by LPS.
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- CAS No.: 2519450-32-7
- Formule: C15H12N4O3S
- Masse moléculaire:328.35
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Chemical Information
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CAS No. 2519450-32-7
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Masse moléculaire 328.35
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Formule C15H12N4O3S
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SMILES
COC1=CC=C(C=C1)C2=NC(C(N3CCS/C3=N\C#N)=O)=CO2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)