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Cat. No.: HY-180278

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CDK6 ligand 1

CDK6 ligand 1 is a ligand for target CDK6 protein for PROTAC. PROTAC CDK6 ligand 2 can be used for the synthesis of PROTAC CDK6 Degrader 1 (HY-180277).

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Formule: C₃₀H₃₈N₈O₃
Masse moléculaire:558.67

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

CDK6 ligand 1 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

CDK6 ligand 1 is a ligand for target CDK6 protein for PROTAC. PROTAC CDK6 ligand 2 can be used for the synthesis of PROTAC CDK6 Degrader 1 (HY-180277)^[1].

IC₅₀ & Target^[1]

CDK6

Voir tous les produits spécifiques à Isoform CDK :

Chemical Information

Masse moléculaire 558.67
Formule C₃₀H₃₈N₈O₃
SMILES

CC(C1=C(C)C(C(N(C1=O)C2CCCC2)=N3)=CN=C3NC(C=C4)=NC=C4N5CCN(CC5)C(C6CCNCC6)=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Jeon E, et al. Selective CDK6 Degradation via the KLHDC2 E3 Ubiquitin Ligase. J Med Chem. 2025 Dec 11;68(23):25539-25568. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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CDK6 ligand 1

Voir tous les produits spécifiques à Isoform CDK

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

CDK6 ligand 1 Related Classifications

HY-180278 Related Classifications