Carboxyaminoimidazole ribotide
Based on 2 publication(s) in Google Scholar
Carboxyaminoimidazole ribotide (CAIR) is a metabolite of E. coli. Carboxyaminoimidazole ribotide can be used to detect distinctive features of E. coli PurE active site and synthesis fungal de novo purine.
For research use only. We do not sell to patients.
- Purity: 98.92%
- CAS No.: 6001-14-5
- Formula: C9H14N3O9P
- Molecular Weight:339.20
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Carboxyaminoimidazole ribotide
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 6001-14-5
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Appearance Solid
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Molecular Weight 339.20
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Formula C9H14N3O9P
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Color Off-white to light yellow
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SMILES
O=C(C1=C(N)N([C@@H]([C@H](O)[C@@H]2O)O[C@@H]2COP(O)(O)=O)C=N1)O
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Synonyms
CAIR; 4-Carboxy-AIR
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Publications (2)
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Journal Impact Factor
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Most Recent
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Nat Commun
ACSS2 drives senescence-associated secretory phenotype by limiting purine biosynthesis through PAICS acetylation. [Abstract]2025 Feb 28;16(1):2071. PMID: 40021646 -
Eur J Hum Genet
Expanding clinical spectrum of PAICS deficiency: Comprehensive analysis of two sibling cases. [Abstract]2025 Jul;33(7):870-877. PMID: 39604553
Solvent & Solubility
H2O : 250 mg/mL (737.03 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.9481 mL | 14.7406 mL | 29.4811 mL | 73.7028 mL |
| 5 mM | 0.5896 mL | 2.9481 mL | 5.8962 mL | 14.7406 mL | |
| 10 mM | 0.2948 mL | 1.4741 mL | 2.9481 mL | 7.3703 mL | |
| 15 mM | 0.1965 mL | 0.9827 mL | 1.9654 mL | 4.9135 mL | |
| 20 mM | 0.1474 mL | 0.7370 mL | 1.4741 mL | 3.6851 mL | |
| 25 mM | 0.1179 mL | 0.5896 mL | 1.1792 mL | 2.9481 mL | |
| 30 mM | 0.0983 mL | 0.4914 mL | 0.9827 mL | 2.4568 mL | |
| 40 mM | 0.0737 mL | 0.3685 mL | 0.7370 mL | 1.8426 mL | |
| 50 mM | 0.0590 mL | 0.2948 mL | 0.5896 mL | 1.4741 mL | |
| 60 mM | 0.0491 mL | 0.2457 mL | 0.4914 mL | 1.2284 mL | |
| 80 mM | 0.0369 mL | 0.1843 mL | 0.3685 mL | 0.9213 mL | |
| 100 mM | 0.0295 mL | 0.1474 mL | 0.2948 mL | 0.7370 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Carboxyaminoimidazole ribotide Related Classifications
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