1001343-34-5
1001343-34-5
Chemical Structure
PLK1-IN-5
- CAS No.: 1001343-34-5
- Formula:C28H39N7O3
- Molecular Weight:521.65
IUPAC Name: 4-((9-cyclopentyl-5,8-dimethyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino)-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide
InChIKey: KZLQLABUFJNPSZ-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C(OC)=C1)NC2=NC=C3C(N(C4CCCC4)C(CC(N3C)=O)C)=N2)NC5CCN(CC5)C
Biological Activity: PLK1-IN-5 is a potent PLK1 inhibitor with an IC50 of < 500 nM. PLK1-IN-5 shows anticancer effects (WO2008113711A1; compound I-4)[1].
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PLK1-IN-5 | PLK1-IN-5 is a potent PLK1 inhibitor with an IC50 of < 500 nM. PLK1-IN-5 shows anticancer effects (WO2008113711A1; compound I-4). | |||||||||||||||||||||
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References
Keywords
