2. Cell Cycle/DNA Damage
  3. Polo-like Kinase (PLK)
  4. PLK1-IN-5

PLK1-IN-5 is a potent PLK1 inhibitor with an IC50 of < 500 nM. PLK1-IN-5 shows anticancer effects (WO2008113711A1; compound I-4).

For research use only. We do not sell to patients.

PLK1-IN-5 Chemical Structure

PLK1-IN-5 Chemical Structure

CAS No. : 1001343-34-5

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PLK1-IN-5 Related Antibodies

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Description

PLK1-IN-5 is a potent PLK1 inhibitor with an IC50 of < 500 nM. PLK1-IN-5 shows anticancer effects (WO2008113711A1; compound I-4)[1].

IC50 & Target[1]

PLK1

<500 nM (IC50)

Molecular Weight

521.65

Formula

C28H39N7O3
CAS No.
SMILES

O=C(C1=CC=C(C(OC)=C1)NC2=NC=C3C(N(C4CCCC4)C(CC(N3C)=O)C)=N2)NC5CCN(CC5)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PLK1-IN-5 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PLK1-IN-51001343-34-5Polo-like Kinase (PLK)PLK1 inhibitoranticancer effectsInhibitorinhibitorinhibit

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