1005201-24-0
1005201-24-0
Chemical Structure
TCS2002
- CAS No.: 1005201-24-0
- Formula:C18H14N2O3S
- Molecular Weight:338.38
IUPAC Name: 2-methyl-5-(3-(4-(methylsulfinyl)phenyl)benzofuran-5-yl)-1,3,4-oxadiazole
InChIKey: RCKYSTKYIVULEK-UHFFFAOYSA-N
SMILES: O=S(C)C1=CC=C(C=C1)C2=COC3=CC=C(C4=NN=C(C)O4)C=C23
Biological Activity: TCS2002 (Compound 9b) is a highly selective, orally bioavailable and potent GSK-3β inhibitor with the IC50 of 35 nM. TCS2002 shows good pharmacokinetic profiles including favorable BBB penetration. TCS2002 can be used for the research of Alzheimer’s disease[1].
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TCS2002 | 99.80% | TCS2002 (Compound 9b) is a highly selective, orally bioavailable and potent GSK-3β inhibitor with the IC50 of 35 nM. TCS2002 shows good pharmacokinetic profiles including favorable BBB penetration. TCS2002 can be used for the research of Alzheimer’s disease. | ||||||||||||||||||||
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