1009365-98-3
1009365-98-3
Chemical Structure
(Rac)-BMS-816336
- CAS No.: 1009365-98-3
- Formula:C21H27NO3
- Molecular Weight:341.44
IUPAC Name: 2-((1R,2r,3S,5r)-6-hydroxy-2-phenyladamantan-2-yl)-1-(3-hydroxyazetidin-1-yl)ethan-1-one
InChIKey: OAAZMUGLOXGVNH-IOWOZSTCSA-N
SMILES: OC1[C@H]2C[C@@H]3[C@@](C4=CC=CC=C4)(CC(N5CC(O)C5)=O)[C@@H](CC1C3)C2
Biological Activity: (Rac)-BMS-816336 (Compound 6n) is a racemate of BMS-816336. (Rac)-BMS-816336 is a potent inhibitor of human and mouse 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme with IC50s of 10 nM and 68 nM, respectively. (Rac)-BMS-816336 has good metabolic stability[1].
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(Rac)-BMS-816336 | 99.91% | (Rac)-BMS-816336 (Compound 6n) is a racemate of BMS-816336. (Rac)-BMS-816336 is a potent inhibitor of human and mouse 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme with IC50s of 10 nM and 68 nM, respectively. (Rac)-BMS-816336 has good metabolic stability. | ||||||||||||||||||||
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References
Keywords
