104146-10-3
Chemical Structure
GCLE
Synonym(s): Cephalosporin G 3-chloromethyl p-methoxybenzyl ester
- CAS. Nr.: 104146-10-3
- Formula:C24H23ClN2O5S
- Molecular Weight:486.97
IUPAC Name: 4-methoxybenzyl (6R,7R)-3-(chloromethyl)-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
InChIKey: KFCMZNUGNLCSJQ-NFBKMPQASA-N
SMILES: O=C(N[C@@H]1C(N2C(C(OCC3=CC=C(OC)C=C3)=O)=C(CS[C@H]12)CCl)=O)CC4=CC=CC=C4
Biological Activity: GCLE (Cephalosporin G 3-chloromethyl p-methoxybenzyl ester) is a SARS-CoV-2 main protease (Mpro) inhibitor with an IC50 of 0.03 μM. GCLE selectively acylates the Cys145 residue of Mpro. GCLE is applicable to research related to COVID-19[1].
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GCLE | ≥97.0% | GCLE (Cephalosporin G 3-chloromethyl p-methoxybenzyl ester) is a SARS-CoV-2 main protease (Mpro) inhibitor with an IC50 of 0.03 μM. GCLE selectively acylates the Cys145 residue of Mpro. GCLE is applicable to research related to COVID-19. | ||||||||||||||||||||
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