1049691-47-5
1049691-47-5
Chemical Structure
NR2F2-IN-1
- CAS No.: 1049691-47-5
- Formula:C17H20ClN3O2S
- Molecular Weight:365.88
InChIKey: PYRMFONFWQTEGD-UHFFFAOYSA-N
SMILES: COC(C(OC)=C1)=CC=C1CCNC2=C3C=C(C)SC3=NC=N2.Cl
Biological Activity: NR2F2-IN-1 is a COUP-TFII (orphan nuclear receptor NR2F2) inhibitor with antitumor activity against prostate cancer. NR2F2-IN-1 directly binds to the COUP-TFII ligand-binding domain and disrupts COUP-TFII interaction with transcription regulators including FOXA1. NR2F2-IN-1 can be used for the research of prostate cancer[1].
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NR2F2-IN-1 | NR2F2-IN-1 is a COUP-TFII (orphan nuclear receptor NR2F2) inhibitor with antitumor activity against prostate cancer. NR2F2-IN-1 directly binds to the COUP-TFII ligand-binding domain and disrupts COUP-TFII interaction with transcription regulators including FOXA1. NR2F2-IN-1 can be used for the research of prostate cancer. | |||||||||||||||||||||
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