1103920-19-9
1103920-19-9
Chemical Structure
Anti-inflammatory agent 8
- CAS No.: 1103920-19-9
- Formula:C18H15N5OS2
- Molecular Weight:381.47
IUPAC Name: 2-(3-methylbenzo[4,5]imidazo[2,1-b]thiazole-2-carbonyl)-N-phenylhydrazine-1-carbothioamide
InChIKey: GJJCPBZXNXVEDO-UHFFFAOYSA-N
SMILES: O=C(C1=C(C)N2C3=CC=CC=C3N=C2S1)NNC(NC4=CC=CC=C4)=S
Biological Activity: Anti-inflammatory agent 8 (compound 13) is a tilomisole-based benzimidazothiazole derivative. Anti-inflammatory agent 8 expresses activity on COX-2 enzyme more than COX-1 with an IC50 of 0.09 nM. Anti-inflammatory agent 8 is orally active[1].
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Anti-inflammatory agent 8 | Anti-inflammatory agent 8 (compound 13) is a tilomisole-based benzimidazothiazole derivative. Anti-inflammatory agent 8 expresses activity on COX-2 enzyme more than COX-1 with an IC50 of 0.09 nM. Anti-inflammatory agent 8 is orally active. | |||||||||||||||||||||
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References
Keywords
