114200-31-6
Chemical Structure
PAOPA
- CAS 番号: 114200-31-6
- Formula:C11H18N4O3
- Molecular Weight:254.29
IUPAC Name: (S)-N-((R)-1-(2-amino-2-oxoethyl)-2-oxopyrrolidin-3-yl)pyrrolidine-2-carboxamide
InChIKey: QXHVGEXNEZRSGG-JGVFFNPUSA-N
SMILES: O=C([C@@H]1CCCN1)N[C@H]2C(N(CC2)CC(N)=O)=O
Biological Activity: PAOPA, an analog of L-proline-l-leucine-glycine amide (PLG) peptide, is an allosteric modulator of Dopamine D2 Receptor. PAOPA can effectively reduce behavioral abnormalities in rodent models of schizophrenia. PAOPA increases the high affinity dopamine D2 receptor and promotes its binding to agonists[1].
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PAOPA | 98.09% | PAOPA, an analog of L-proline-l-leucine-glycine amide (PLG) peptide, is an allosteric modulator of Dopamine D2 Receptor. PAOPA can effectively reduce behavioral abnormalities in rodent models of schizophrenia. PAOPA increases the high affinity dopamine D2 receptor and promotes its binding to agonists. | ||||||||||||||||||||
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PAOPA (Standard) | ≥98% | PAOPA (Standard) is the analytical standard of PAOPA (HY-103423). This product is intended for research and analytical applications. PAOPA, an analog of L-proline-l-leucine-glycine amide (PLG) peptide, is an allosteric modulator of Dopamine D2 Receptor. PAOPA can effectively reduce behavioral abnormalities in rodent models of schizophrenia. PAOPA increases the high affinity dopamine D2 receptor and promotes its binding to agonists. | ||||||||||||||||||||
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