116521-53-0
Chemical Structure
ME 2303
Synonym(s): FAD 104
- CAS No.: 116521-53-0
- Formula:C34H37FO15
- Molecular Weight:704.65
IUPAC Name: 7-(2-((2S,4S)-4-(((2R,3R,4R,5S,6S)-3-fluoro-4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)-2-oxoethoxy)-7-oxoheptanoic acid
InChIKey: PQMIPLRIRFVQJZ-QBYYVRQOSA-N
SMILES: OC1=C2C([C@H](C[C@@](C(COC(CCCCCC(O)=O)=O)=O)(O)C2)O[C@@]3([H])[C@@H]([C@@H]([C@H](O)[C@H](C)O3)O)F)=C(O)C4=C1C(C5=CC=CC(OC)=C5C4=O)=O
Biological Activity: ME 2303 (FAD 104) is a fluoro-pyranosyl adriamycin analogue with anti-tumor potential. ME 2303 can inhibit the proliferation of acute undifferentiated myeloblastic leukemia (AML) blast cells in a dose-dependent manner. ME 2303 can be used for the study of acute undifferentiated myeloblastic leukemia (AML)[1].
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ME 2303 | ME 2303 (FAD 104) is a fluoro-pyranosyl adriamycin analogue with anti-tumor potential. ME 2303 can inhibit the proliferation of acute undifferentiated myeloblastic leukemia (AML) blast cells in a dose-dependent manner. ME 2303 can be used for the study of acute undifferentiated myeloblastic leukemia (AML). | |||||||||||||||||||||
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