ME 2303
ME 2303 (FAD 104) is a fluoro-pyranosyl adriamycin analogue with anti-tumor potential. ME 2303 can inhibit the proliferation of acute undifferentiated myeloblastic leukemia (AML) blast cells in a dose-dependent manner. ME 2303 can be used for the study of acute undifferentiated myeloblastic leukemia (AML).
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 116521-53-0
- Fòrmula: C34H37FO15
- Peso molecular:704.65
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
Chemical Information
-
No. CAS 116521-53-0
-
Peso molecular 704.65
-
Fòrmula C34H37FO15
-
SMILES
OC1=C2C([C@H](C[C@@](C(COC(CCCCCC(O)=O)=O)=O)(O)C2)O[C@@]3([H])[C@@H]([C@@H]([C@H](O)[C@H](C)O3)O)F)=C(O)C4=C1C(C5=CC=CC(OC)=C5C4=O)=O
-
Synonyms
FAD 104
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
-
Cell Viability Determination by MTT Colorimetric Assay
The following protocol uses the MTT colorimetric assay as a classic literature-established method for assessing cell viability/metabolic activity in cultured mammalian cells. MTT[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] is reduced by metabolically active cells to a colored formazan product; the amount of formazan is quantified spectrophotometrically and provides an indirect measure of metabolically active viable cells. Importantly, MTT reduction reflects cellular oxidoreductase/metabolic activity rather than an absolute direct count of living cells, so changes in cellular metabolism can alter the signal independently of cell number.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)