117442-28-1
Chemical Structure
Xenin-8
- CAS No.: 117442-28-1
- Formula:C51H79N15O9
- Molecular Weight:1046.27
IUPAC Name: L-histidyl-L-prolyl-L-lysyl-L-arginyl-L-prolyl-L-tryptophyl-L-isoleucyl-L-leucine
InChIKey: QNDRYLNMRDPBTI-OBOKMFOZSA-N
SMILES: O=C([C@H]1N(CCC1)C([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@H]2N(CCC2)C([C@@H](N)CC3=CNC=N3)=O)=O)=O)=O)N[C@H](C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)CC(C)C)=O)=O)CC4=CNC5=C4C=CC=C5
Biological Activity: Xenin-8, a C-terminal octapeptide, is a biologically active fragment of Xenin. Xenin is a 25-amino acid peptide of the neurotensin/xenopsin family. Xenin-8 stimulates basal insulin secretion and potentiates the insulin response to glucose in a dose-dependent manner (EC50=0.16 nM)[1].
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Xenin-8 | Xenin-8, a C-terminal octapeptide, is a biologically active fragment of Xenin. Xenin is a 25-amino acid peptide of the neurotensin/xenopsin family. Xenin-8 stimulates basal insulin secretion and potentiates the insulin response to glucose in a dose-dependent manner (EC50=0.16 nM). | |||||||||||||||||||||
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Keywords
