1181681-43-5
1181681-43-5
Chemical Structure
fluoro-Dapagliflozin
- CAS No.: 1181681-43-5
- Formula:C21H24ClFO5
- Molecular Weight:410.86
IUPAC Name: (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-5-fluoro-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4-diol
InChIKey: VYRXTNZYAGBKPS-ADAARDCZSA-N
SMILES: O[C@H]1[C@H](C2=CC(CC3=CC=C(C=C3)OCC)=C(C=C2)Cl)O[C@@H]([C@H]([C@@H]1O)F)CO
Biological Activity: fluoro-Dapagliflozin, a structural analog of Dapagliflozin, is a selective SGLT2 inhibitor with Ki values of 5.3 nM and 330 nM for SGLT2 and SGLT1, respectively. fluoro-Dapagliflozin blocks glucose transport and glucose-coupled currents[1].
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fluoro-Dapagliflozin | fluoro-Dapagliflozin, a structural analog of Dapagliflozin, is a selective SGLT2 inhibitor with Ki values of 5.3 nM and 330 nM for SGLT2 and SGLT1, respectively. fluoro-Dapagliflozin blocks glucose transport and glucose-coupled currents. | |||||||||||||||||||||
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References
Keywords
