fluoro-Dapagliflozin
fluoro-Dapagliflozin, a structural analog of Dapagliflozin, is a selective SGLT2 inhibitor with Ki values of 5.3 nM and 330 nM for SGLT2 and SGLT1, respectively. fluoro-Dapagliflozin blocks glucose transport and glucose-coupled currents.
For research use only. We do not sell to patients.
- CAS No.: 1181681-43-5
- Formula: C21H24ClFO5
- Molecular Weight:410.86
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
hSGLT2 5.3 nM (Ki) |
hSGLT1 330 nM (Ki) |
Chemical Information
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CAS No. 1181681-43-5
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Molecular Weight 410.86
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Formula C21H24ClFO5
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SMILES
O[C@H]1[C@H](C2=CC(CC3=CC=C(C=C3)OCC)=C(C=C2)Cl)O[C@@H]([C@H]([C@@H]1O)F)CO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)