1191908-24-3
Chemical Structure
ADRA1D receptor antagonist 1 free base
- CAS No.: 1191908-24-3
- Formula:C15H13ClN4O
- Molecular Weight:300.74
IUPAC Name: (R)-5-chloro-1-(1-(3-cyanophenyl)ethyl)-2-imino-1,2-dihydropyridine-3-carboxamide
InChIKey: CDJPHTNUARAVMH-SECBINFHSA-N
SMILES: O=C(C1=CC(Cl)=CN([C@@H](C2=CC=CC(C#N)=C2)C)C1=N)N
Biological Activity: ADRA1D receptor antagonist 1 (free base) (compound (R)-9s) is an orally active, potent and selective human α1D-adrenoceptor (α1D-AR) antagonist (Ki=1.6 nM). ADRA1D receptor antagonist 1 (free base) dose-dependently inhibits bladder contraction with an IC30 value of 15 nM. ADRA1D receptor antagonist 1 (free base) can be used in studies of overactive bladder disorders such as urinary urgency, frequency and incontinence.
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ADRA1D receptor antagonist 1 free base | ADRA1D receptor antagonist 1 (free base) (compound (R)-9s) is an orally active, potent and selective human α1D-adrenoceptor (α1D-AR) antagonist (Ki=1.6 nM). ADRA1D receptor antagonist 1 (free base) dose-dependently inhibits bladder contraction with an IC30 value of 15 nM. ADRA1D receptor antagonist 1 (free base) can be used in studies of overactive bladder disorders such as urinary urgency, frequency and incontinence. | |||||||||||||||||||||
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