1195768-06-9
1195768-06-9
Chemical Structure
Dabrafenib Mesylate
Synonym(s): GSK2118436 Mesylate; GSK 2118436B
- CAS No.: 1195768-06-9
- Formula:C24H24F3N5O5S3
- Molecular Weight:615.67
IUPAC Name: N-(3-(5-(2-aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide methanesulfonate
InChIKey: YKGMKSIHIVVYKY-UHFFFAOYSA-N
SMILES: CC(C)(C)C1=NC(C2=C(F)C(NS(C3=C(F)C=CC=C3F)(=O)=O)=CC=C2)=C(C4=CC=NC(N)=N4)S1.CS(=O)(O)=O
Biological Activity: Dabrafenib Mesylate is a potent and selective Raf kinase inhibitor with IC50s of 0.6 and 5.0 nM for RafV600E and c-Raf, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Dabrafenib Mesylate | 99.94% | Dabrafenib Mesylate is a potent and selective Raf kinase inhibitor with IC50s of 0.6 and 5.0 nM for RafV600E and c-Raf, respectively. | ||||||||||||||||||||
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Dabrafenib Mesylate (Standard) | ≥98% | Dabrafenib (Mesylate) (Standard) is the analytical standard of Dabrafenib (Mesylate). This product is intended for research and analytical applications. Dabrafenib Mesylate is a potent and selective Raf kinase inhibitor with IC50s of 0.6 and 5.0 nM for RafV600E and c-Raf, respectively. | ||||||||||||||||||||
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