1216698-89-3
Chemical Structure
Monoethylglycinexylidide-d6
Synonym(s): MEGX-d6; Norlidocaine-d6
- CAS No.: 1216698-89-3
- Formula:C12H12D6N2O
- Molecular Weight:212.32
IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol (S)-2-(3-benzoylphenyl)propanoate-3,3,3-d3
InChIKey: WRMRXPASUROZGT-XERRXZQWSA-N
SMILES: CCNCC(NC1=C(C=CC=C1C([2H])([2H])[2H])C([2H])([2H])[2H])=O
Biological Activity: Monoethylglycinexylidide-d6 (MEGX-d6; Norlidocaine-d6) is the deuterated-labeled Monoethylglycinexylidide (HY-118167). Monoethylglycinexylidide is the major metabolite of Lidocaine (HY-B0185), produced via oxidative metabolism by cytochrome P-450 enzymes in the liver. Monoethylglycinexylidide can be used for research on liver cirrhosis[1][2].
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Monoethylglycinexylidide-d6 | Monoethylglycinexylidide-d6 (MEGX-d6; Norlidocaine-d6) is the deuterated-labeled Monoethylglycinexylidide (HY-118167). Monoethylglycinexylidide is the major metabolite of Lidocaine (HY-B0185), produced via oxidative metabolism by cytochrome P-450 enzymes in the liver. Monoethylglycinexylidide can be used for research on liver cirrhosis. | |||||||||||||||||||||
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Monoethylglycinexylidide (Standard) | ≥98% | Monoethylglycinexylidide (Standard) is the analytical standard of Monoethylglycinexylidide (HY-118167). This product is intended for research and analytical applications. Monoethylglycinexylidide (MEGX; Norlidocaine) is the major metabolite of Lidocaine (HY-B0185), produced via oxidative metabolism by cytochrome P-450 enzymes in the liver. Monoethylglycinexylidide can be used for research on liver cirrhosis. | ||||||||||||||||||||
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Nor Lidocaine-d5 hydrochloride | Nor Lidocaine-d5 (hydrochloride) is the deuterium labeled Nor Lidocaine hydrochloride. | |||||||||||||||||||||
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Monoethylglycinexylidide | 99.69% | Monoethylglycinexylidide (MEGX; Norlidocaine) is the major metabolite of Lidocaine (HY-B0185), produced via oxidative metabolism by cytochrome P-450 enzymes in the liver. Monoethylglycinexylidide can be used for research on liver cirrhosis. | ||||||||||||||||||||
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References
- [1]. Oni G, et al. Comparison of five commonly-available, lidocaine-containing topical anesthetics and their effect on serum levels of lidocaine and its metabolite monoethylglycinexylidide (MEGX). Aesthetic surgery journal. 2012 May;32(4):495-503. [Content Brief]
- [2]. Elin RJ, et al. Assessment of monoethylglycinexylidide as measure of liver function for patients with chronic viral hepatitis. Clinical chemistry. 1997 Oct;43(10):1952-7. [Content Brief]
