121785-71-5
Chemical Structure
(21R)-Argatroban
- CAS No.: 121785-71-5
- Formula:C23H36N6O5S
- Molecular Weight:508.63
IUPAC Name: (2R,4R)-1-((S)-5-((diaminomethylene)amino)-2-(((R)-3-methyl-1,2,3,4-tetrahydroquinoline)-8-sulfonamido)pentanoyl)-4-methylpiperidine-2-carboxylic acid
InChIKey: KXNPVXPOPUZYGB-XYVMCAHJSA-N
SMILES: O=C(N1[C@H](C[C@@H](CC1)C)C(O)=O)[C@H](CCCNC(N)=N)NS(=O)(C2=C3C(C[C@H](CN3)C)=CC=C2)=O
Biological Activity: (21R)-Argatroban is a diastereoisomer of Argatroban (HY-B0375). (21R)-Argatroban is also an inhibitor of thrombin with anticoagulant activity. (21R)-Argatroban can be used for research related to anticoagulation[1][2].
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(21R)-Argatroban | (21R)-Argatroban is a diastereoisomer of Argatroban (HY-B0375). (21R)-Argatroban is also an inhibitor of thrombin with anticoagulant activity. (21R)-Argatroban can be used for research related to anticoagulation. | |||||||||||||||||||||
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- [1]. Ferraboschi P, et al. Crystallographic, spectroscopic, and theoretical investigation of the efficiently separated 21R and 21S-diastereoisomers of argatroban. Chirality. 2013 Dec;25(12):871-82. [Content Brief]
- [2]. Rawson TE, et al. Separation of 21-(R)- and 21-(S)-argatroban: solubility and activity of the individual diastereoisomers. J Pharm Sci. 1993 Jun;82(6):672-3. [Content Brief]
Keywords