(21R)-Argatroban
(21R)-Argatroban is a diastereoisomer of Argatroban (HY-B0375). (21R)-Argatroban is also an inhibitor of thrombin with anticoagulant activity. (21R)-Argatroban can be used for research related to anticoagulation.
For research use only. We do not sell to patients.
- CAS No.: 121785-71-5
- Formula: C23H36N6O5S
- Molecular Weight:508.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Caco-2 | Inhibition |
5.02 %
Compound: ARGATROBAN
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Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging
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10.21203/rs.3.rs-23951/v1 |
Chemical Information
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CAS No. 121785-71-5
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Molecular Weight 508.63
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Formula C23H36N6O5S
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SMILES
O=C(N1[C@H](C[C@@H](CC1)C)C(O)=O)[C@H](CCCNC(N)=N)NS(=O)(C2=C3C(C[C@H](CN3)C)=CC=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ferraboschi P, et al. Crystallographic, spectroscopic, and theoretical investigation of the efficiently separated 21R and 21S-diastereoisomers of argatroban. Chirality. 2013 Dec;25(12):871-82. [Content Brief]
[2]. Rawson TE, et al. Separation of 21-(R)- and 21-(S)-argatroban: solubility and activity of the individual diastereoisomers. J Pharm Sci. 1993 Jun;82(6):672-3. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(21R)-Argatroban Related Classifications
HY-116363 Related Classifications
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