1219592-01-4
1219592-01-4
Chemical Structure
Pazopanib-d6
Synonym(s): GW786034-d6
- CAS 番号: 1219592-01-4
- Formula:C21H17D6N7O2S
- Molecular Weight:443.55
IUPAC Name: 2-methyl-5-((4-((methyl-d3)(3-methyl-2-(methyl-d3)-2H-indazol-6-yl)amino)pyrimidin-2-yl)amino)benzenesulfonamide
InChIKey: CUIHSIWYWATEQL-LIJFRPJRSA-N
SMILES: CC1=CC=C(NC2=NC=CC(N(C3=CC4=NN(C(C)=C4C=C3)C([2H])([2H])[2H])C([2H])([2H])[2H])=N2)C=C1S(N)(=O)=O
Biological Activity: Pazopanib-d6 is the deuterium labeled Pazopanib. Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with IC50s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively.
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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Pazopanib-d6 | 98.0% | Pazopanib-d6 is the deuterium labeled Pazopanib. Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with IC50s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively. | ||||||||||||||||||||
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Pazopanib (Standard) | ≥98% | Pazopanib (Standard) is the analytical standard of Pazopanib. This product is intended for research and analytical applications. Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with IC50s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively. | ||||||||||||||||||||
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Pazopanib-13C,d3 | Pazopanib-13C,d3 is the deuterium and 13C labeled Pazopanib. Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with IC50s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively. | |||||||||||||||||||||
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Pazopanib-d3 | Pazopanib-d3 (GW786034-d3) is deuterium labeled Pazopanib. Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with IC50s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively. | |||||||||||||||||||||
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Pazopanib | 99.91% | Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with IC50s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively. | ||||||||||||||||||||
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