121999-68-6
Chemical Structure
C20 Sphingomyelin (d18:1/20:0)
Synonym(s): N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine; SM(d18:1/20:0)
- CAS No.: 121999-68-6
- Formula:C43H87N2O6P
- Molecular Weight:759.13
IUPAC Name: 2-(4-acetylphenyl)-2,2-difluoroacetic acid
InChIKey: AADLTHQNYQJHQV-SVLGDMRNSA-N
SMILES: CCCCCCCCCCCCCCCCCCCC(N[C@H]([C@H](O)/C=C/CCCCCCCCCCCCC)COP(OCC[N+](C)(C)C)([O-])=O)=O
Biological Activity: C20 Sphingomyelin (d18:1/20:0) (N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine; SM(d18:1/20:0)) is a naturally occurring sphingolipid. C20 Sphingomyelin (d18:1/20:0) levels are upregulated in the hippocampus of streptozotocin (HY-13753)-induced diabetic rats and in human plasma, positively correlating with insulin resistance in obese humans. C20 Sphingomyelin (d18:1/20:0) is also upregulated in the liver of a mouse model of Niemann-Pick C1 disease, a neurodegenerative cholesterol sphingolipid lysosomal storage disorder.
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C20 Sphingomyelin (d18:1/20:0) | C20 Sphingomyelin (d18:1/20:0) (N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine; SM(d18:1/20:0)) is a naturally occurring sphingolipid. C20 Sphingomyelin (d18:1/20:0) levels are upregulated in the hippocampus of streptozotocin (HY-13753)-induced diabetic rats and in human plasma, positively correlating with insulin resistance in obese humans. C20 Sphingomyelin (d18:1/20:0) is also upregulated in the liver of a mouse model of Niemann-Pick C1 disease, a neurodegenerative cholesterol sphingolipid lysosomal storage disorder. | |||||||||||||||||||||
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