122946-43-4
122946-43-4
Chemical Structure
Telmesteine
- CAS No.: 122946-43-4
- Formula:C7H11NO4S
- Molecular Weight:205.23
IUPAC Name: (R)-3-(ethoxycarbonyl)thiazolidine-4-carboxylic acid
InChIKey: XBJWOGLKABXFJE-YFKPBYRVSA-N
SMILES: O=C(O)[C@H]1N(CSC1)C(OCC)=O
Biological Activity: Telmesteine is an amucolitic agent. Telmesteine has anti-protease activity. Telmesteine inhibits LPS-induced NO production in RAW264.7 cells. Telmesteine can be used for research of inflammation, such as acute and chronic bronchitis and obstructive airways disease[1][2].
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Telmesteine | Telmesteine is an amucolitic agent. Telmesteine has anti-protease activity. Telmesteine inhibits LPS-induced NO production in RAW264.7 cells. Telmesteine can be used for research of inflammation, such as acute and chronic bronchitis and obstructive airways disease. | |||||||||||||||||||||
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References
- [1]. Lee J, et al. Absorption, distribution, metabolism and excretion of telmesteine, a mucolitic agent, in rat. Xenobiotica. 2003 Jul;33(7):755-65. [Content Brief]
- [2]. Xuetao Xu, et al. Evaluation of the anti-inflammatory properties of telmesteine on inflammation-associated skin diseases. RSC Adv., 2017, 7, 34699-34704.
