1244040-64-9

Tetrazine-Ph-NHCO-C3-NHS ester Chemical Structure
1244040-64-9

Chemical Structure

Tetrazine-Ph-NHCO-C3-NHS ester

  • CAS No.: 1244040-64-9
  • Formula:C18H18N6O5
  • Molecular Weight:398.37

IUPAC Name: 2,5-dioxopyrrolidin-1-yl 5-((4-(1,2,4,5-tetrazin-3-yl)benzyl)amino)-5-oxopentanoate

InChIKey: QDUUJWMNSUXICN-UHFFFAOYSA-N

SMILES: O=C(CCCC(ON1C(CCC1=O)=O)=O)NCC2=CC=C(C3=NN=CN=N3)C=C2

Biological Activity: Tetrazine-Ph-NHCO-C3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Tetrazine-Ph-NHCO-C3-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

Cat. No. Product Name Purity Description Pricing
HY-133479
Tetrazine-Ph-NHCO-C3-NHS ester 98.40% Tetrazine-Ph-NHCO-C3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Tetrazine-Ph-NHCO-C3-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References