124649-78-1
Chemical Structure
(-)-Dihydroguaiaretic acid
- CAS No.: 124649-78-1
- Formula:C20H26O4
- Molecular Weight:330.42
IUPAC Name: tert-butyl 3-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)propanoate
InChIKey: ADFOLUXMYYCTRR-ZIAGYGMSSA-N
SMILES: COC(C=C1C[C@@H](C)[C@H](C)CC2=CC(OC)=C(C=C2)O)=C(C=C1)O
Biological Activity: (-)-Dihydroguaiaretic acid is a Lipoxygenase inhibitor that has antioxidant activity. (-)-Dihydroguaiaretic acid inhibits the oxidation of unsaturated fatty acids and removes free radicals. (-)-Dihydroguaiaretic acid also has anticancer activity with an IC50 value of 7.49 μM (A549 cells)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(-)-Dihydroguaiaretic acid | 98.79% | (-)-Dihydroguaiaretic acid is a Lipoxygenase inhibitor that has antioxidant activity. (-)-Dihydroguaiaretic acid inhibits the oxidation of unsaturated fatty acids and removes free radicals. (-)-Dihydroguaiaretic acid also has anticancer activity with an IC50 value of 7.49 μM (A549 cells). | ||||||||||||||||||||
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- [1]. Yamauchi S, et al. Antioxidant activity of butane type lignans, secoisolariciresinol, dihydroguaiaretic acid, and 7,7'-oxodihydroguaiaretic acid. Biosci Biotechnol Biochem. 2008 Nov;72(11):2981-6. [Content Brief]
- [2]. Davis R A, et al. Isolation, structure elucidation and cytotoxic evaluation of endiandrin B from the Australian rainforest plant Endiandra anthropophagorum[J]. Bioorganic & medicinal chemistry, 2009, 17(3): 1387-1392.
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