126223-28-7
Chemical Structure
Ginsenoside Rg4
- CAS No.: 126223-28-7
- Formula:C42H70O12
- Molecular Weight:767.00
IUPAC Name: (2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-2-(((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-((Z)-6-methylhepta-2,5-dien-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-6-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol
InChIKey: QOMBXPYXWGTFNR-KRPFXEAISA-N
SMILES: C[C@]12[C@@]3(C)[C@@]([H])([C@H](CC3)/C(C)=C\C/C=C(C)\C)[C@@H](C[C@@]1([C@]4(C)[C@@]([H])([C@H](C2)O[C@]5([C@H](O[C@]6([C@H](O)[C@H](O)[C@H]([C@@H](O6)C)O)[H])[C@@H](O)[C@@H]([C@H](O5)CO)O)[H])C([C@H](CC4)O)(C)C)[H])O
Biological Activity: Ginsenoside Rg4 is an orally active protopanaxatriol type ginsenoside. Ginsenoside Rg4 can activate PI3K, AKT and GSK-3β signaling. Ginsenoside Rg4 can inhibit ROS and inflammatory cytokine levels. Ginsenoside Rg4 can be used for the researches of inflammation, infection and metabolic disease, such as sepsis and lung inflammation[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ginsenoside Rg4 | 99.94% | Ginsenoside Rg4 is an orally active protopanaxatriol type ginsenoside. Ginsenoside Rg4 can activate PI3K, AKT and GSK-3β signaling. Ginsenoside Rg4 can inhibit ROS and inflammatory cytokine levels. Ginsenoside Rg4 can be used for the researches of inflammation, infection and metabolic disease, such as sepsis and lung inflammation. | ||||||||||||||||||||
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- [1]. Kim GO, et al. Inhibitory Activities of Rare Ginsenoside Rg4 on Cecal Ligation and Puncture-Induced Sepsis. Int J Mol Sci. 2022 Sep 16;23(18):10836. [Content Brief]
- [2]. Lee YH, et al. Ginsenoside Rg4 Enhances the Inductive Effects of Human Dermal Papilla Spheres on Hair Growth Via the AKT/GSK-3β/β-Catenin Signaling Pathway. J Microbiol Biotechnol. 2021 Jul 28;31(7):933-941. [Content Brief]
- [3]. Wonhwa Lee, et al. Pulmonary Protective Functions of Rare Ginsenoside Rg4 on Particulate Matter-induced Inflammatory Responses. Biotechnology and Bioprocess Engineering 24: 445-453 (2019).
Keywords
