1268874-09-4
Chemical Structure
Matriptase-IN-2
- CAS No.: 1268874-09-4
- Formula:C33H35Cl2F6N5O7S
- Molecular Weight:830.62
InChIKey: HCTPOLRWOSFUBB-LPCSYZHESA-N
SMILES: OC(C(F)(F)F)=O.ClC1=C(C2=CC(S(N[C@H](C(N3CCC(CC3)CCN)=O)CC4=CC(C(N)=N)=CC=C4)(=O)=O)=CC=C2)C=CC(Cl)=C1.OC(C(F)(F)F)=O
Biological Activity: Matriptase-IN-2 is a secondary amide inhibitor of matriptase derived from sulfonylated 3-amidinophenylalanine, with a Ki value of 5 nM. Matriptase acts as a novel initiator of cartilage matrix degradation in osteoarthritis, and Matriptase-IN-2 inhibits matriptase-mediated cartilage degradation. Matriptase-IN-2 is applicable for the research of osteoarthritis[1].
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Matriptase-IN-2 | 99.87% | Matriptase-IN-2 is a secondary amide inhibitor of matriptase derived from sulfonylated 3-amidinophenylalanine, with a Ki value of 5 nM. Matriptase acts as a novel initiator of cartilage matrix degradation in osteoarthritis, and Matriptase-IN-2 inhibits matriptase-mediated cartilage degradation. Matriptase-IN-2 is applicable for the research of osteoarthritis. | ||||||||||||||||||||
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Keywords
