1280738-47-7
Chemical Structure
PT4
- CAS No.: 1280738-47-7
- Formula:C18H14N4O2
- Molecular Weight:318.33
IUPAC Name: 2-(2-(4-phenyl-1H-1,2,3-triazol-1-yl)ethyl)isoindoline-1,3-dione
InChIKey: BLQILMHASZUUHU-UHFFFAOYSA-N
SMILES: O=C1N(CCN2N=NC(C3=CC=CC=C3)=C2)C(C4=C1C=CC=C4)=O
Biological Activity: PT4 is a therapeutic agent against Cutaneous leishmaniasis (CL). PT4 is effective against both species of Leishmania, with IC50s of 125.18 and 233.18 μM for L. amazonensis and L. braziliensis, respectively. PT4 decreases of mitochondrial membrane potential and increases production of reactive oxygen species, which leads to parasite death. PT4 has a potent in vivo anti-inflammatory activity[1].
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PT4 | PT4 is a therapeutic agent against Cutaneous leishmaniasis (CL). PT4 is effective against both species of Leishmania, with IC50s of 125.18 and 233.18 μM for L. amazonensis and L. braziliensis, respectively. PT4 decreases of mitochondrial membrane potential and increases production of reactive oxygen species, which leads to parasite death. PT4 has a potent in vivo anti-inflammatory activity. | |||||||||||||||||||||
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Keywords
