1330188-81-2
1330188-81-2
Chemical Structure
Norcyclizine-d8
Synonym(s): 1-(Diphenylmethyl)piperazine-d8; 1-Benzhydrylpiperazine-d8
- CAS No.: 1330188-81-2
- Formula:C17H12D8N2
- Molecular Weight:260.40
IUPAC Name: 1-benzhydrylpiperazine-2,2,3,3,5,5,6,6-d8
InChIKey: NWVNXDKZIQLBNM-FUEQIQQISA-N
SMILES: [2H]C1([2H])C([2H])([2H])NC([2H])([2H])C([2H])([2H])N1C(C2=CC=CC=C2)C3=CC=CC=C3
Biological Activity: Norcyclizine-d8 is the deuterium labeled Norcyclizine[1].
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Norcyclizine-d8 | Norcyclizine-d8 is the deuterium labeled Norcyclizine. | |||||||||||||||||||||
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Norcyclizine | Norcyclizine is a piperazine compound that can be used for the synthesis of antimicrobial agents. 1-Benzhydrylpiperazine derivatives have been found to enhance the antibacterial activity of β-lactam antibiotics (Oxacillin, HY-B0925A) against Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA). This enhancement is likely achieved by inhibiting the allosteric site of PBP2a. Additionally, 1-Benzhydrylpiperazine can also serve as a pharmacological scaffold for the synthesis of anticancer agents. | |||||||||||||||||||||
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References
Keywords
