1337531-36-8
1337531-36-8
Chemical Structure
GSK2606414
- CAS No.: 1337531-36-8
- Formula:C24H20F3N5O
- Molecular Weight:451.44
IUPAC Name: 1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)indolin-1-yl)-2-(3-(trifluoromethyl)phenyl)ethan-1-one
InChIKey: SIXVRXARNAVBTC-UHFFFAOYSA-N
SMILES: NC1=C2C(N(C)C=C2C3=CC4=C(N(C(CC5=CC=CC(C(F)(F)F)=C5)=O)CC4)C=C3)=NC=N1
Biological Activity: GSK2606414 is a cell-permeable and orally available protein kinase R-like endoplasmic reticulum (ER) kinase (PERK) inhibitor with an IC50 of 0.4 nM.
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GSK2606414 | 99.91% | GSK2606414 is a cell-permeable and orally available protein kinase R-like endoplasmic reticulum (ER) kinase (PERK) inhibitor with an IC50 of 0.4 nM. | ||||||||||||||||||||
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GSK2606414 (Standard) | ≥98% | GSK2606414 (Standard) is the analytical standard of GSK2606414 (HY-18072). This product is intended for research and analytical applications. GSK2606414 is a cell-permeable and orally available protein Kinase R-like endoplasmic reticulum (ER) Kinase (PERK) inhibitor with an IC50 of 0.4 nM. | ||||||||||||||||||||
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