1351941-69-9

Sacibertinib Chemical Structure
1351941-69-9

Chemical Structure

Sacibertinib

  • CAS No.: 1351941-69-9
  • Formula:C32H31ClN6O4
  • Molecular Weight:599.08

IUPAC Name: (S,E)-N-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-((tetrahydrofuran-3-yl)oxy)quinolin-6-yl)-4-(dimethylamino)but-2-enamide

InChIKey: ZGYIXVSQHOKQRZ-COIATFDQSA-N

SMILES: CN(C)C/C=C/C(NC1=CC(C(NC2=CC(Cl)=C(C=C2)OCC3=CC=CC=N3)=C(C#N)C=N4)=C4C=C1O[C@H]5CCOC5)=O

Biological Activity: Sacibertinib is a tyrosine kinase (Trk) inhibitor with EC50 value of 110 nM and 244 nM for EGFR-TK phosphorylation and HER2, respectively. Antineoplastic activity[1].

Cat. No. Product Name Purity Description Pricing
HY-147303 		Sacibertinib Sacibertinib is a tyrosine kinase (Trk) inhibitor with EC50 value of 110 nM and 244 nM for EGFR-TK phosphorylation and HER2, respectively. Antineoplastic activity.
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