1352335-71-7
Chemical Structure
Xentry
- CAS No.: 1352335-71-7
- Formula:C33H60N10O8S
- Molecular Weight:756.96
InChIKey: OPINSJOKVIGQCK-HXJPVCIYSA-N
SMILES: O=C(N[C@@H](CS)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N1[C@@H](CCC1)C(N[C@@H](C(C)C)C(NCC(O)=O)=O)=O)=O)=O)=O)[C@H](CC(C)C)N
Biological Activity: Xentry is a cell-penetrating peptide (CCP) consisting of only 7 amino acids of hepatitis B virus: LCLRPVG. Xentry-linked anti-B-raf antibodies and siRNAs demonstrates the capability to kill B-raf-dependent melanoma cells. Xentry alone or conjugated to β-galactosidase leads to its delivery to most tissues in mice, except circulating blood cells. Xentry can be used for the delivery of large molecules (antibodies, siRNA, enzymes) [1].
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Xentry | Xentry is a cell-penetrating peptide (CCP) consisting of only 7 amino acids of hepatitis B virus: LCLRPVG. Xentry-linked anti-B-raf antibodies and siRNAs demonstrates the capability to kill B-raf-dependent melanoma cells. Xentry alone or conjugated to β-galactosidase leads to its delivery to most tissues in mice, except circulating blood cells. Xentry can be used for the delivery of large molecules (antibodies, siRNA, enzymes) . | |||||||||||||||||||||
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Keywords
