1353570-40-7
1353570-40-7
Chemical Structure
γ-Secretase modulator 13
- CAS No.: 1353570-40-7
- Formula:C22H23FN6S
- Molecular Weight:422.52
IUPAC Name: N-(2-ethyl-4,5,6,7-tetrahydro-2H-indazol-3-yl)-4-(3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl)thiazol-2-amine
InChIKey: AKJWVOIRNRIEEP-UHFFFAOYSA-N
SMILES: FC1=C(N2C=NC(C)=C2)C=CC(C3=CSC(NC4=C5C(CCCC5)=NN4CC)=N3)=C1
Biological Activity: γ-Secretase modulator 13 (compound 4) is a gamma-secretase modulator (GSMs) that inhibits the production of the aggregated amyloid β-peptide Aβ42 with an IC50 value of 163 nM. γ-Secretase modulator 13 can be used in the study of Alzheimer's disease[1].
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γ-Secretase modulator 13 | γ-Secretase modulator 13 (compound 4) is a gamma-secretase modulator (GSMs) that inhibits the production of the aggregated amyloid β-peptide Aβ42 with an IC50 value of 163 nM. γ-Secretase modulator 13 can be used in the study of Alzheimer's disease. | |||||||||||||||||||||
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References
Keywords
