135383-54-9
135383-54-9
Chemical Structure
Monomethyl auristatin E intermediate-6
- CAS No.: 135383-54-9
- Formula:C20H29NO5
- Molecular Weight:363.45
IUPAC Name: tert-butyl (4S,5S)-4-(((benzyloxy)carbonyl)amino)-5-methyl-3-oxoheptanoate
InChIKey: OBDXBUWPBDVKEB-KSSFIOAISA-N
SMILES: CC[C@H](C)[C@H](NC(OCC1=CC=CC=C1)=O)C(CC(OC(C)(C)C)=O)=O
Biological Activity: Monomethyl auristatin E intermediate-6 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
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Monomethyl auristatin E intermediate-6 | Monomethyl auristatin E intermediate-6 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs). | |||||||||||||||||||||
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References
