136098-04-9
Chemical Structure
Heparin disaccharide I-H trisodium
- CAS No.: 136098-04-9
- Formula:C12H16NNa3O16S2
- Molecular Weight:563.35
InChIKey: WDZNBOXILUXNDK-BDEDDMKQSA-K
SMILES: O=S(OC[C@@H](O)[C@H]([C@H](O)[C@@H](N)C=O)O[C@H]1[C@@H]([C@H](C=C(O1)C(O[Na])=O)O)OS(=O)(O[Na])=O)(O[Na])=O
Biological Activity: Heparin disaccharide I-H trisodium (Compound SHS-5) is a heparin-derived disaccharide. Heparin disaccharide I-H trisodium blocks the spontaneous secretion of IL-8 and IL-1β in intestinal epithelial cells at the post-translational stage without reducing mRNA expression levels or intracellular contents. Heparin disaccharide I-H trisodium exhibits dose-dependent anti-inflammatory activity in intestinal epithelial cell models[1].
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Heparin disaccharide I-H trisodium | Heparin disaccharide I-H trisodium (Compound SHS-5) is a heparin-derived disaccharide. Heparin disaccharide I-H trisodium blocks the spontaneous secretion of IL-8 and IL-1β in intestinal epithelial cells at the post-translational stage without reducing mRNA expression levels or intracellular contents. Heparin disaccharide I-H trisodium exhibits dose-dependent anti-inflammatory activity in intestinal epithelial cell models. | |||||||||||||||||||||
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