138387-16-3
Chemical Structure
Doxepin-d3
- CAS No.: 138387-16-3
- Formula:C19H18D3NO
- Molecular Weight:282.39
IUPAC Name: (Z)-3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N-methyl-N-(methyl-d3)propan-1-amine
InChIKey: ODQWQRRAPPTVAG-QRYZPGCSSA-N
SMILES: [2H]C([2H])([2H])N(C)CC/C=C1C2=CC=CC=C2COC3=CC=CC=C3/1
Biological Activity: Doxepin-d3 is the deuterium labeled Doxepin (HY-B0725A). Doxepin s an orally active tricyclic antidepressant agent. Doxepin is a potent and selective histamine receptor H1 antagonist. Doxepin is also a potent CYP450 inhibitor and significantly inhibits CYP450 2C19 and 1A2. Doxepin inhibits reuptake of serotonin and norepinephrine as a tricyclic antidepressant. Doxepin has therapeutic effects in atopic dermatitis, chronic urticarial, can improve cognitive processes, protect central nervous system. Doxepin has also been proposed as a protective factor against oxidative stress.
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Doxepin-d3 | Doxepin-d3 is the deuterium labeled Doxepin (HY-B0725A). Doxepin s an orally active tricyclic antidepressant agent. Doxepin is a potent and selective histamine receptor H1 antagonist. Doxepin is also a potent CYP450 inhibitor and significantly inhibits CYP450 2C19 and 1A2. Doxepin inhibits reuptake of serotonin and norepinephrine as a tricyclic antidepressant. Doxepin has therapeutic effects in atopic dermatitis, chronic urticarial, can improve cognitive processes, protect central nervous system. Doxepin has also been proposed as a protective factor against oxidative stress. | |||||||||||||||||||||
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Doxepin | 99.66% | Doxepin inhibits reuptake of serotonin and norepinephrine as a tricyclic antidepressant. Doxepin has therapeutic effects in atopic dermatitis，chronic urticarial，can improve cognitive processes， protect central nervous system. Doxepin has also been proposed as a protective factor against oxidative stress. | ||||||||||||||||||||
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Keywords
