141443-40-5
Chemical Structure
Antibiotic AB023b
- CAS. Nr.: 141443-40-5
- Formula:C32H52O8
- Molecular Weight:564.75
IUPAC Name: (17E,19E,21E,23E,25E)-3-ethyl-4,6,10,12,14,16-hexahydroxy-15,27,28-trimethyloxacyclooctacosa-17,19,21,23,25-pentaen-2-one
InChIKey: JJDUHQRKYHRVNV-VYZGRHQBSA-N
SMILES: O=C1OC(C)C(C)/C=C/C=C/C=C/C=C/C=C/C(O)C(C)C(O)CC(O)CC(O)CCCC(O)CC(O)C1CC
Biological Activity: Antibiotic AB023b is part of macrocyclic pentaene antibiotic complex, forming the main components with Antibiotic AB023a (HY-137084). Antibiotic AB023b exhibits antifungal activity against Candida albicans, and plant pathogenic fungi, Botrytis cinerea, Fusarium moniliforme and Pythium ultimum[1][2].
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Antibiotic AB023b | Antibiotic AB023b is part of macrocyclic pentaene antibiotic complex, forming the main components with Antibiotic AB023a (HY-137084). Antibiotic AB023b exhibits antifungal activity against Candida albicans, and plant pathogenic fungi, Botrytis cinerea, Fusarium moniliforme and Pythium ultimum. | |||||||||||||||||||||
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- [1]. Bortolo R, et al., AB023, novel polyene antibiotics. II. Isolation and structure determination. J Antibiot (Tokyo). 1993 Feb;46(2):255-64. [Content Brief]
- [2]. Cidaria D, et al., AB023, novel polyene antibiotics. I. Taxonomy of the producing organism, fermentation and antifungal activity. J Antibiot (Tokyo). 1993 Feb;46(2):251-4. [Content Brief]
Keywords
