1417312-35-6
1417312-35-6
Chemical Structure
ECL1i
- CAS No.: 1417312-35-6
- Formula:C36H60N8O9S
- Molecular Weight:780.97
InChIKey: QFKVHWUTXCBAEV-STZPNDCUSA-N
SMILES: OC([C@@H](CS)NC([C@@H](CCCCN)NC([C@@H](CC(C)C)NC([C@H](NC([C@@H]([C@@H](O)C)NC(CNC([C@H](N)CC(C)C)=O)=O)=O)CC1=CC=CC=C1)=O)=O)=O)=O
Biological Activity: ECL1i is an allosteric, selective CCR2 inhibitor. ECL1i specifically inhibits CCL2-/CCR2-mediated chemotaxis. ECL1i interferes with CCR2-positive cell recruitment and attenuates disease progression in experimental autoimmune encephalomyelitis[1].
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ECL1i | ECL1i is an allosteric, selective CCR2 inhibitor. ECL1i specifically inhibits CCL2-/CCR2-mediated chemotaxis. ECL1i interferes with CCR2-positive cell recruitment and attenuates disease progression in experimental autoimmune encephalomyelitis. | |||||||||||||||||||||
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References
Keywords
