1434517-02-8
1434517-02-8
Chemical Structure
IMPDH2-IN-2
- CAS No.: 1434517-02-8
- Formula:C21H15Cl2N3O3
- Molecular Weight:428.27
IUPAC Name: (S)-2-(2,3-dichlorophenoxy)-N-(2-(pyridin-4-yl)benzo[d]oxazol-5-yl)propanamide
InChIKey: HRXGXBGJVNUGSX-LBPRGKRZSA-N
SMILES: C[C@H](OC1=CC=CC(Cl)=C1Cl)C(NC2=CC=C(OC(C3=CC=NC=C3)=N4)C4=C2)=O
Biological Activity: IMPDH2-IN-2 is an inhibitor of Mycobacterium tuberculosis inosine 5′-monophosphate dehydrogenase 2 (MtbIMPDH2) with a Ki,app value of 14 nM. IMPDH2-IN-2 blocks guanine nucleotide biosynthesis and exhibits antibacterial activity against Mycobacterium tuberculosis. IMPDH2-IN-2 can be used for research on tuberculosis[1].
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IMPDH2-IN-2 | 99.89% | IMPDH2-IN-2 is an inhibitor of Mycobacterium tuberculosis inosine 5′-monophosphate dehydrogenase 2 (MtbIMPDH2) with a Ki,app value of 14 nM. IMPDH2-IN-2 blocks guanine nucleotide biosynthesis and exhibits antibacterial activity against Mycobacterium tuberculosis. IMPDH2-IN-2 can be used for research on tuberculosis. | ||||||||||||||||||||
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